2016 46:1213–37.įurugori E, Hirayama R, Nakamura KI, Kammori M, Esaki Y, Takubo K. Telomere length maintenance and cardio-metabolic disease prevention through exercise training. Cigarette smoking and telomere length: a systematic review of 84 studies and meta-analysis. 2008 7:451–8.Īstuti Y, Wardhana A, Watkins J, Wulaningsih W, PILAR Research Network. Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study. Hunt SC, Chen W, Gardner JP, Kimura M, Srinivasan SR, Eckfeldt JH, et al. Leukocyte telomere length and mortality in the Cardiovascular Health Study. 2005 5:197–203.įitzpatrick AL, Kronmal RA, Kimura M, Gardner JP, Psaty BM, Jenny NS, et al.
Telomeres as biomarkers for ageing and age-related diseases. Conclusionīaltic sea diet, Mediterranean diet, and diet’s inflammatory potential seem to have only little impact on telomere length and telomere attrition in elderly Finnish men and women. Adherence to BSDS and DII did not associate with LTL change in men or women. No association between mMED and LTL change was found in men. Higher mMED at baseline (2001–2004) was associated with slightly faster LTL shortening during the follow-up (standardized ß −0.08, 95% CI −0.15, −0.01). ResultsīSDS, mMED, and DII did not associate with LTL in the cross-sectional analysis in men or women. Association between the dietary patterns and LTL were analysed by general linear models with appropriate contrasts. LTL was measured twice, in 2001–2004 and in 2011–2013 by quantitative real-time polymerase chain reaction. Baltic sea diet score (BSDS), modified Mediterranean diet score (mMED), and dietary inflammatory index (DII ®) were calculated based on a 128-item food frequency questionnaire (FFQ) collected in 2001–2004. Participants were 456 men and 590 women whose birth settled in between 19 and who participated in the Helsinki Birth Cohort Study. The setting was longitudinal and observational. The aim was to study if overall dietary pattern is associated with leukocyte telomere length (LTL) or faster telomere attrition or both. Little evidence exists regarding the relationship between dietary patterns and telomere length, especially derived applying longitudinal design. Telomeres are repeats of DNA that contain the sequence TTAGGG at the ends of each chromosome, and their function is to protect DNA from damage.
0 kommentar(er)
